Intestinal microbiota and infant health in early life / 国际儿科学杂志

ABSTRACT

The establishment and development of the intestinal microbiota in early life is critical to the development of intestinal immune system,digestive function,metabolic function,and central nervous system function in infants.The first 1000 days of life is a critical period for the establishment of intestinal microbiota,which is susceptible to many factors.The disorder of intestinal microbiota in this period will increase the risk of some diseases in the long-term life.In this review,we will describe the main physiological functions of the early-life microbiota and its role in programming future health of infants.We also will describe the establishment and development of the intestinal microbiota in early life and its main drivers.