Clinical observation of 6 severe COVID-19 patients treated with plasma exchange or tocilizumab / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 227-231, 2020.
Article
ي Zh
| WPRIM
| ID: wpr-828548
المكتبة المسؤولة:
WPRO
ABSTRACT
OBJECTIVE@#To observe the clinical effect of plasma exchange and tocilizumab in treatment of patients with severe coronavirus disease 2019 (COVID-19).@*METHODS@#Six patients with severe COVID-19 admitted in First Affiliated Hospital of Bengbu Medical College from January 25 to February 25, 2020. Three patients were treated with plasma exchange and three patients were treated with tocilizumab. The effect on excessive inflammatory reaction of plasma exchange and tocilizumab was observed.@*RESULTS@#The C-reactive protein (CRP) and IL-6 levels were significantly decreased and the lymphocyte and prothrombin time were improved in 3 patients after treatment with plasma exchange; while inflammation level was not significantly decreased, and lymphocyte and prothrombin time did not improve in 3 patients treated with tocilizumab.@*CONCLUSIONS@#For severe COVID-19 patients with strong inflammatory reaction, plasma exchange may be preferred.
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Plasma Exchange
/
Pneumonia, Viral
/
Prothrombin Time
/
Reference Standards
/
Therapeutics
/
Blood
/
Treatment Outcome
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Coronavirus Infections
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Allergy and Immunology
/
Pandemics
المحددات:
Humans
اللغة:
Zh
مجلة:
Journal of Zhejiang University. Medical sciences
السنة:
2020
نوع:
Article