Expression of metastasis-associated molecules CD99, FKBP5, FLJ13576 in primary cell renal cell carcinoma / 第二军医大学学报
Academic Journal of Second Military Medical University
; (12): 360-363, 2010.
Article
ي Zh
| WPRIM
| ID: wpr-840601
المكتبة المسؤولة:
WPRO
ABSTRACT
Objective: To evaluate the expression of metastasis-associated molecules CD99, FKBP5 and FLJ13576 in primary clear cell renal cell carcinoma (ccRCC). Methods: Semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) was used to examine the differential expression of CD99, FKBP5, and FLJ13576 in the primary ccRCC tissues and the corresponding adjacent normal renal tissues. Results: The positive rates of CD99, FKBP5, and FLJ13576 in the primary ccRCC tissues were 72%, 60% and 48%, respectively, which were significantly higher than those in the adjacent normal renal tissues(28%, 24%, and 16%, P<0.05). Conclusion: Cancer metastasis-associated molecules CD99, FKBP5 and FLJ13576 are highly expressed in the primary ccRCC tissues, which might be associated with the development and progression of renal cancer. CD99, FKBP5 and FLJ13576 may serve as potential markers for detection of ccRCC.
النص الكامل:
1
الفهرس:
WPRIM
اللغة:
Zh
مجلة:
Academic Journal of Second Military Medical University
السنة:
2010
نوع:
Article