Progress of exosome in the diagnosis and treatment of brain metastasis of breast cancer / 肿瘤
Tumor
; (12): 361-370, 2020.
Article
ي Zh
| WPRIM
| ID: wpr-848190
المكتبة المسؤولة:
WPRO
ABSTRACT
Breast cancer is the most common malignant tumor about women in China, and brain metastasis may occur in about 5% to 20% of breast cancer patients. Exosome is a kind of vesicle secreted into the extracellular environment. In the recent years’ study, it has been found that exosome may participate in the occurrence and development of brain metastasis, thus they can be regarded as the diagnosis of breast cancer brain metastasis potential biomarker, and play important roles in the drug delivery carrier. Also, they serve as therapeutic target in the treatment of breast cancer. Therefore, this review focuses on the role of exosome in the diagnosis and treatment of breast cancer brain metastasis in order to provide potential biomarkers, such as protein and RNA, and lay a foundation for further research of effective targeted therapeutic.
النص الكامل:
1
الفهرس:
WPRIM
نوع الدراسة:
Diagnostic_studies
اللغة:
Zh
مجلة:
Tumor
السنة:
2020
نوع:
Article