Attention to Bacillus Calmette-Guerin disease / 中华实用儿科临床杂志

ABSTRACT

Pediatrics tuberculosis remains a global public health problem, despite substantial progress in the diagnosis and treatment of this disease due to the improvement of social living standards and increasing global attention.Bacillus Calmette-Guerin (BCG) is recognized as one of the important means to prevent severe tuberculosis infection.As a country with high burden of tuberculosis, China classifies BCG as a vaccine for routine immunization of children in the national immunization programs.Most infants have no adverse reactions after BCG vaccination with, but a small number of babies will develop BCG infection, disseminated infection and even death in severe cases.In this article, the common adverse reactions were described, and it appealed that attention should be paid to the primary immunodeficiency diseases behind severe abnormal reactions.