The contribution of absorption of integral nanocrystals to enhancement of oral bioavailability of quercetin
Acta Pharmaceutica Sinica B
; (6): 978-988, 2021.
Article
ي En
| WPRIM
| ID: wpr-881179
المكتبة المسؤولة:
WPRO
ABSTRACT
In this study, self-discriminating hybrid nanocrystals was utilized to explore the biological fate of quercetin hybrid nanocrystals (QT-HNCs) with diameter around 280 nm (QT-HNCs-280) and 550 nm (QT-HNCs-550) following oral and intravenous administration and the contribution of integral nanocrystals to oral bioavailability enhancement of QT was estimated by comparing the absolute exposure of integral QT-HNCs and total QT in the liver. Results showed that QT-HNCs could reside
النص الكامل:
1
الفهرس:
WPRIM
اللغة:
En
مجلة:
Acta Pharmaceutica Sinica B
السنة:
2021
نوع:
Article