Oxaliplatin-Induced Immune-Mediated Thrombocytopenia: A Case Report / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
; : 949-953, 2015.
Article
ي En
| WPRIM
| ID: wpr-90542
المكتبة المسؤولة:
WPRO
ABSTRACT
Oxaliplatin is a third-generation platinum derivative used for metastatic or advanced colorectal cancer treatment. Although myelosuppression is the most common cause of oxaliplatin-induced thrombocytopenia, rare cases of oxaliplatin-induced immune-mediated thrombocytopenia are reported. We report a case of a 57-year-old woman with colon cancer who developed gum bleeding and petechiae after oxaliplatin infusion. Laboratory tests revealed grade 4 thrombocytopenia and grade 4 neutropenia. She recovered from the thrombocytopenia and accompanying neutropenia within 4 days with no recurrence following discontinuation of oxaliplatin. Physicians need to be aware of the risk of severe acute thrombocytopenia following oxaliplatin administration.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Platinum
/
Purpura
/
Recurrence
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Thrombocytopenia
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Colorectal Neoplasms
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Colonic Neoplasms
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Gingiva
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Hemorrhage
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Neutropenia
المحددات:
Female
/
Humans
اللغة:
En
مجلة:
Cancer Research and Treatment
السنة:
2015
نوع:
Article