Application of high-dose intravenous immunoglobulin in the treatment of severe dermatoses / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12): 455-459, 2022.
Article
ي Zh
| WPRIM
| ID: wpr-933562
المكتبة المسؤولة:
WPRO
ABSTRACT
High-dose intravenous immunoglobulin (IVIG) has emerged as an effective treatment option for some refractory and severe dermatoses with few adverse reactions. The Fab and Fc fragments of IgG can exert anti-inflammatory effect by mediating specific downstream reactions via binding to a variety of autoantigens, autoantibodies and complements. This review summarizes action mechanisms of IVIG, focuses on the progress towards its application in severe dermatoses (such as severe drug eruption, refractory dermatomyositis and autoimmune bullous diseases) and special populations, as well as its adverse reactions.
النص الكامل:
1
الفهرس:
WPRIM
اللغة:
Zh
مجلة:
Chinese Journal of Dermatology
السنة:
2022
نوع:
Article