The Effects of Multi-Growth Factors-Containing Cream on Post-Thyroidectomy Scars: A Preliminary Study
Annals of Dermatology
; : 314-320, 2017.
Article
ي En
| WPRIM
| ID: wpr-93896
المكتبة المسؤولة:
WPRO
ABSTRACT
BACKGROUND:
Growth factors play important roles in wound healing. However, the evidence for the effects of growth factors on post-thyroidectomy scars is limited.OBJECTIVE:
We performed a prospective study to assess the preventive and therapeutic effect of a multi-growth factor (MGF)-containing cream on post-thyroidectomy scars.METHODS:
Twenty-one patients with thyroidectomy scars applied MGF cream twice a day. We assessed the changes in erythema, pigmentation, skin elasticity, and skin hydration status using the erythema index, melanin index, cutometer, and corneometer, respectively. In addition, Vancouver scar scale (VSS) and patient satisfaction were assessed at 10 days after surgery (baseline), 2 weeks, 6 weeks, and 12 weeks after baseline.RESULTS:
The mean total VSS scores were significantly lower at 6 weeks (3.24±1.51 vs. 1.91±1.38) and 12 weeks (3.24±1.51 vs. 1.71±1.59) compared to the baseline. The degree of pigmentation was significantly lower at 12 weeks compared to the baseline, and the skin elasticity, and the skin hydration status were significantly higher at 12 weeks compared to the baseline. Over 85% of the patients were satisfied with the use of MGF cream without any adverse effect.CONCLUSION:
MGF cream might have additive or supportive effect for scar formation after thyroidectomy.Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Skin
/
Thyroidectomy
/
Wound Healing
/
Pigmentation
/
Skin Pigmentation
/
Prospective Studies
/
Cicatrix
/
Patient Satisfaction
/
Intercellular Signaling Peptides and Proteins
/
Elasticity
نوع الدراسة:
Observational_studies
المحددات:
Humans
اللغة:
En
مجلة:
Annals of Dermatology
السنة:
2017
نوع:
Article