Levosulpiride-induced Parkinsonim
Journal of the Korean Neurological Association
; : 418-421, 2003.
Article
ي Ko
| WPRIM
| ID: wpr-95810
المكتبة المسؤولة:
WPRO
ABSTRACT
The present report discusses four cases of chronic renal failure, which developed symptoms of parkinsonism in response to levosulpiride. The temporal relationship between levosulpiride discontinuation and the disappearance of parkinsonism suggests a causal link. In addition, decreased striatal dopamine transporter bindings assessed by [I-123] IPT SPECT were observed in two patients suggesting that a dopamine blocking agent causes the dysfunction of nigrostriatal dopaminergic neurons and that such injury may be involved in the pathogenesis of drug-induced parkinsonism.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Dopamine
/
Tomography, Emission-Computed, Single-Photon
/
Parkinsonian Disorders
/
Dopamine Plasma Membrane Transport Proteins
/
Dopaminergic Neurons
/
Kidney Failure, Chronic
المحددات:
Humans
اللغة:
Ko
مجلة:
Journal of the Korean Neurological Association
السنة:
2003
نوع:
Article