Rifampicin-Induced Thrombocytopenia: A case report
Philippine Journal of Internal Medicine
; : 62-66, 2021.
Article
ي En
| WPRIM
| ID: wpr-961162
المكتبة المسؤولة:
WPRO
ABSTRACT
INTRODUCTION@#The worldwide prevalence of adverse drug reactions (ADR) to anti-TB medication ranges from 8% to 85%. Major adverse reactions include hepatic, renal, and hematologic disorders of which, Rifampicin-induced thrombocytopenia is one of these rare complications.@*CASE@#A 58-year-old Filipino male developed respiratory and gastrointestinal bleeding with a severe drop in platelet count after several days of anti-tuberculosis (anti-TB) medications. The patient had oral mucosal petechiae, blood-streaked sputum, and epistaxis. The symptoms progressed to the formation of small adherent clots beneath the tongue, gum bleeding, melena, massive epistaxis, and hemoptysis with continued intake of the anti-TB drugs. The patient had anemia, normal WBC and differential count, and thrombocytopenia of 3 x 10
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الفهرس:
WPRIM
الموضوع الرئيسي:
Rifampin
/
Thrombocytopenia
/
Tuberculosis
/
Blood Platelets
اللغة:
En
مجلة:
Philippine Journal of Internal Medicine
السنة:
2021
نوع:
Article