A novel sesquiterpenoid from Curcuma longa L / 药学学报
Acta Pharmaceutica Sinica
; (12): 3603-3607, 2022.
Article
ي Zh
| WPRIM
| ID: wpr-964321
المكتبة المسؤولة:
WPRO
ABSTRACT
A new compound was isolated from the 95% ethanolic extract of the rhizomes of Curcuma longa L. using silica gel column chromatography, medium pressure liquid chromatography, and semi-preparative high performance liquid chromatography. The structure and absolute configuration of the compound was elucidated by HR-ESI-MS, NMR, and electronic circular dichroism (ECD) calculations. It is a novel sesquiterpenoid, which is named as isoturmeronol B (1). The carbon skeleton of compound 1 is similar to that of bisabolane-type sesquiterpenoid. The only difference is that the methyl group at C-4 in bisabolene-type sesquiterpenoid is migrated to C-5 in compound 1. Besides, the anti-inflammatory and antioxidant activities of the compound 1 were evaluated. The results showed that 1 has no anti-inflammatory and antioxidant activities.
النص الكامل:
1
الفهرس:
WPRIM
اللغة:
Zh
مجلة:
Acta Pharmaceutica Sinica
السنة:
2022
نوع:
Article