Recent studies on dilated cardiomyopathy caused by TTN mutations in children / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 217-222, 2023.
Article
ي Zh
| WPRIM
| ID: wpr-971063
المكتبة المسؤولة:
WPRO
ABSTRACT
The mutations of TTN gene that encodes titin are the most common mutation type among the genetic causes of dilated cardiomyopathy (DCM). This article reviews the worldwide studies on potential molecular pathogenesis (transcription, post-translational modification, etc.), clinical phenotypes, and gene therapies of pediatric DCM caused by TTN mutations, with the hope of providing a reference for the precision treatment of pediatric DCM caused by TTN mutations.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Phenotype
/
Cardiomyopathy, Dilated
/
Genetic Therapy
/
Connectin
/
Mutation
المحددات:
Humans
اللغة:
Zh
مجلة:
Chinese Journal of Contemporary Pediatrics
السنة:
2023
نوع:
Article