Engineering microbial consortia through synthetic biology approach / 生物工程学报
Chinese Journal of Biotechnology
; (12): 2517-2545, 2023.
Article
ي Zh
| WPRIM
| ID: wpr-981215
المكتبة المسؤولة:
WPRO
ABSTRACT
There are a large number of natural microbial communities in nature. Different populations inside the consortia expand the performance boundary of a single microbial population through communication and division of labor, reducing the overall metabolic burden and increasing the environmental adaptability. Based on engineering principles, synthetic biology designs or modifies basic functional components, gene circuits, and chassis cells to purposefully reprogram the operational processes of the living cells, achieving rich and controllable biological functions. Introducing this engineering design principle to obtain structurally well-defined synthetic microbial communities can provide ideas for theoretical studies and shed light on versatile applications. This review discussed recent progresses on synthetic microbial consortia with regard to design principles, construction methods and applications, and prospected future perspectives.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Microbial Consortia
/
Synthetic Biology
/
Microbiota
/
Models, Theoretical
اللغة:
Zh
مجلة:
Chinese Journal of Biotechnology
السنة:
2023
نوع:
Article