Progress in Application of Heparin Coating in Blood Contact Medical Devices / 中国医疗器械杂志
Chinese Journal of Medical Instrumentation
; (6): 288-293, 2023.
Article
ي Zh
| WPRIM
| ID: wpr-982230
المكتبة المسؤولة:
WPRO
ABSTRACT
Blood compatibility is the main restriction of blood-contacting medical devices in clinical application, especially long-term blood-contacting medical devices will stimulate the immune defense mechanism of the host, resulting in thrombosis. Heparin anticoagulant coating links heparin molecules to the surface of medical device product materials, improves the compatibility between the material surface interface and the body, and reduces the host immune defense reactions. This study reviews the structure and biological properties of heparin, the market application status of heparin-coated medical products, the insufficiency and improvement of heparin coating, which can provide a reference for the application research of blood contact medical devices.
Key words
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Surface Properties
/
Thrombosis
/
Heparin
/
Coated Materials, Biocompatible
/
Anticoagulants
المحددات:
Humans
اللغة:
Zh
مجلة:
Chinese Journal of Medical Instrumentation
السنة:
2023
نوع:
Article