The relationship between the degradation of actin and the postmortem interval in rats / 法医学杂志
Journal of Forensic Medicine
; (6): 165-171, 2008.
Article
ي Zh
| WPRIM
| ID: wpr-983373
المكتبة المسؤولة:
WPRO
ABSTRACT
OBJECTIVE@#To observe the degradation of actin in cardiac muscle, brain and skeletal muscle of rats after death and to find an objective parameter interval (PMI) estimation.@*METHODS@#Twenty eight clear Sprague Dawley rats put into an artificial climate incubator (set at 20 degrees C) for 0, 24, 48, 72, The actin contents in the above tissues were quantitated by Western-blot Pro Plus 5.0 image analysis system, and were then statistically analyzed@*RESULTS@#Actin content in all these tissues decreased gradually with prolonged differences between the groups was statistically significant (P < 0.05), with fastest, then the lung, the spleen, the liver, the kidney, the cardiac muscle order. There was a strong correlation between actin degradation and determination (R2) exceeded 0.75 in all these tissues.@*CONCLUSION@#degradation, the actin contents in cardiac muscle, liver, spleen, lung, kindey, rats decreased gradually with prolonged PMI, which may potentially be PMI estimation.
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Postmortem Changes
/
Time Factors
/
Brain
/
Actins
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Rats, Sprague-Dawley
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Death
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Forensic Pathology
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Liver
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Myocardium
المحددات:
Animals
اللغة:
Zh
مجلة:
Journal of Forensic Medicine
السنة:
2008
نوع:
Article