Forensic Investigation of Goldeneye™ DNA ID 22NC Kit / 法医学杂志
Journal of Forensic Medicine
; (6): 280-283, 2015.
Article
ي Zh
| WPRIM
| ID: wpr-984000
المكتبة المسؤولة:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the genetic data of 21 autosomal STR included in Goldeneye™ DNA ID 22NC Kit in Chinese Han nationality and to evaluate the forensic application.@*METHODS@#By detected 500 unrelated healthy individuals in Chinese Han nationality of East China with Goldeneye™ DNA ID 22NC Kit, allele frequencies, population genetics parameters and linkage disequilibrium information of the 21 autosomal STR were statistically analyzed.@*RESULTS@#In the 21 autosomal STR, no deviations from Hardy-Weinberg equilibrium were detected and all loci were independent form each other. DP values of 21 autosomal STR were all above 0.85, and the combined discrimination power was 1-3.616 5 x 10(-26). Combined mean exclusion chance of this system in duo cases was 1-2.786 81 x10(-6), in trio cases was 1-8.545 82 x 10(-1).@*CONCLUSION@#Twenty-one autosomal STR included in Goldeneye™ DNA ID 22NC Kit are highly polymorphic in the Han nationality. Combined with Goldeneye™ DNA ID 20A Kit, the kit can satisfy the needs for full-sibling testing and facilitate the solution of this kind of case tools.
النص الكامل:
1
الفهرس:
WPRIM
الموضوع الرئيسي:
Polymorphism, Genetic
/
Reagent Kits, Diagnostic
/
Ethnicity
/
Genetic Markers
/
China
/
Asian People
/
Alleles
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Forensic Genetics
/
Genetic Loci
/
Gene Frequency
المحددات:
Humans
البلد/الأقليم حسب الموضوع:
Asia
اللغة:
Zh
مجلة:
Journal of Forensic Medicine
السنة:
2015
نوع:
Article