Research progress of fluoride on non-skeletal injury in multiple systems of the body / 中华地方病学杂志

ABSTRACT

Fluorine is an essential trace element for human body. Appropriate amount of fluorine can have a certain positive impact on the body, but long-term intake of excessive fluorine will cause damage to the body, which is an important cause of endemic fluorosis. The main feature of fluorosis is skeletal injury to the bones and teeth of the body. In recent years, the research of non-skeletal injury has been increasingly paid attention by research scholars. This paper summarized the non-skeletal injury of fluorine to urinary, digestive, nervous, circulatory, reproductive, immune systems and other systems, providing a reference for fluorosis-related studies other than skeletal injury.