There is no evident correlation between interleukin-10 gene polymorphisms and periportal fibrosis regression after specific treatment
Rev. Soc. Bras. Med. Trop
; 49(6): 781-785, Dec. 2016. tab
Article
in En
| LILACS
| ID: biblio-1041384
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
We evaluated the associations between interleukin-10 (IL-10) gene polymorphisms -G1082A/-C819T/-C592A and periportal fibrosis regression after specific treatment for schistosomiasis.METHODS:
This retrospective cohort study involved 125 Brazilian patients infected with Schistosomiasis mansoni, who were followed up for 2 years after specific treatment to estimate the probability of periportal fibrosis regression.RESULTS:
There was no evidence of associations between IL-10 polymorphisms and periportal fibrosis regression after treatment.CONCLUSIONS:
There was no evidence of associations between gene promoter polymorphisms of IL-10 and the regression of periportal fibrosis in this Brazilian population.Key words
Full text:
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Index:
LILACS
Main subject:
Schistosomiasis mansoni
/
Interleukin-10
/
Peritoneal Fibrosis
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2016
Type:
Article