Your browser doesn't support javascript.
loading
Cafeteria diet in breastfeeding dams promotes anxiolytic effects, accumulation of adipose tissue, and impacts offspring development / La dieta de la cafetería en las madres que amamantan promueve los efectos ansiolíticos y la acumulación de tejido adiposo, y afecta el desarrollo de la descendencia
Rocha-Gomes, Arthur; Escobar T, Amanda; Fernandes G, Letícia; Sena, Jéssica; Alves da-Silva, Alexandre; Rodrigues L, Mayara; Andrade V, Nísia; Stuckert-Seixas, Sérgio; Regina R, Tania.
  • Rocha-Gomes, Arthur; Federal University of Valleys of Jequitinhonha and Mucuri. Postgraduate Program in Pharmaceutical Sciences. Alto da Jacuba. BR
  • Escobar T, Amanda; Federal University of Valleys of Jequitinhonha and Mucuri. Postgraduate Program in Pharmaceutical Sciences. Alto da Jacuba. BR
  • Fernandes G, Letícia; Federal University of Valley of Jequitinhonha and Mucuri. Department of Nutrition. Alto da Jacuba. BR
  • Sena, Jéssica; Federal University of Valley of Jequitinhonha and Mucuri. Department of Nutrition. Alto da Jacuba. BR
  • Alves da-Silva, Alexandre; Federal University of Valley of Jequitinhonha and Mucuri. Department of Nutrition. Alto da Jacuba. BR
  • Rodrigues L, Mayara; Federal University of Valley of Jequitinhonha and Mucuri. Department of Nutrition. Alto da Jacuba. BR
  • Andrade V, Nísia; Federal University of Valley of Jequitinhonha and Mucuri. Department of Nutrition. Alto da Jacuba. BR
  • Stuckert-Seixas, Sérgio; Federal University of Valley of Jequitinhonha and Mucuri. Department of Pharmacy. Alto da Jacuba. BR
  • Regina R, Tania; Federal University of Valley of Jequitinhonha and Mucuri. Department of Nutrition. Alto da Jacuba. BR
Rev. chil. nutr ; 46(6): 735-745, dic. 2019. tab, graf
Article in English | LILACS | ID: biblio-1058136
ABSTRACT
The aim of this study was to evaluate the nutritional and behavioral effects of a cafeteria diet in dams during the breastfeeding period and in their offspring from weaning until early adulthood (70 days old). Pregnant Wistar rats were fed a chow diet until delivery. Postnatally (D0), litters were culled to 8 pups and lactating dams received control (CTRL n= 6) or cafeteria (CAF n= 6) diets and water ad libitum. At the end of the breastfeeding period, male offspring were placed in individual boxes receiving the same treatment from their respective dams (CTRL or CAF) until adulthood (70 days). All nutritional and behavioral evaluations were performed with the dams (n= 12) during the breastfeeding phase and with the male offspring (n= 24) after weaning to adulthood. CAF dams demonstrated a lower caloric and protein intake; higher intake of fats; loss of weight; greater accumulation of adipose tissue; and an anxiolytic effect. CAF male offspring showed lower caloric intake; higher intake of fats; and accumulation of adipose tissue. In addition, these animals continued to have decreased body weight, body length and tibia-femur length in relation to CTRL. In dams, a cafeteria diet promoted alterations in body composition and anxiety, and in offspring the diet resulted in adequate development.
RESUMEN
El objetivo de este estudio fue evaluar los efectos nutricionales y de comportamiento de la dieta de la cafetería en las madres durante el período de lactancia materna y en su descendencia desde el destete hasta la edad adulta temprana (70 días de edad). Ratas Wistar embarazadas fueron alimentadas con una dieta estándar hasta el parto. Postnatalmente (D0), las camadas se ajustaron en 8 crías y las madres lactantes recibieron las dietas control (CTRL n= 6) o cafetería (CAF n= 6) además de agua ad libitum. Al final del período de lactancia materna, las proles machos fueron colocados en cajas individuales recibiendo el mismo tratamiento de sus respectivas madres (CTRL o CAF) hasta la edad adulta (70 días). Todas las evaluaciones nutricionales y comportamentales se realizaron con las madres (n= 12) durante la fase de lactancia y con la prole masculina (n= 24) después del destete hasta la edad adulta. Las madres CAF demostraron una menor ingesta calórica y proteica; mayor ingestión de grasas; pérdida de peso; mayor acumulación de tejido adiposo; y un efecto ansiolítico. La prole masculina CAF presentó menor consumo calórico; mayor ingestión de grasas; y la acumulación de tejido adiposo. Además, estos animales presentaron menor peso corporal, longitud corporal, y longitud de la tibia-fémur, en relación a CTRL. En las madres, la dieta de cafetería promovió cambios en la composición corporal y ansiedad, y en la prole la dieta comprometió el desarrollo adecuado.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Diet / Feeding Behavior Type of study: Etiology study / Prognostic study Limits: Animals / Pregnancy Language: English Journal: Rev. chil. nutr Journal subject: Nutritional Sciences Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Valley of Jequitinhonha and Mucuri/BR / Federal University of Valleys of Jequitinhonha and Mucuri/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Diet / Feeding Behavior Type of study: Etiology study / Prognostic study Limits: Animals / Pregnancy Language: English Journal: Rev. chil. nutr Journal subject: Nutritional Sciences Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Valley of Jequitinhonha and Mucuri/BR / Federal University of Valleys of Jequitinhonha and Mucuri/BR