Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study
São Paulo med. j
;
138(1): 19-26, Jan.-Feb. 2020. tab, graf
Article
in English
| LILACS
| ID: biblio-1099388
ABSTRACT
ABSTRACT BACKGROUND:
Studies have shown that physical activity levels can be inversely associated with high-sensitivity C-reactive protein (hs-CRP) levels. However, the amount of physical activity required to maintain normal hs-CRP levels is still a matter for speculation.OBJECTIVE:
To identify the amount of physical activity necessary to discriminate the hs-CRP levels in adults. DESIGN ANDSETTING:
Cross-sectional study at six teaching and research institutions.METHODS:
The study sample comprised 10,231 adults aged 35 to 74 years who were participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Receiver operating characteristic (ROC) curves were constructed to compare the amount of physical activity in two domains (leisure time and commuting) with hs-CRP levels. The sensitivity and specificity were calculated to identify the best cutoff for physical activity level that would be needed to maintain normal levels of hs-CRP (< 3 mg/l).RESULTS:
The area under the ROC curve was only statistically significant for discriminating normal levels of hs-CRP according to the amount of physical activity when the two study domains were added together. The accumulated physical activity level of 200 minutes/week was the best cutoff for discriminating normal levels of hs-CRP in adults of both sex.CONCLUSIONS:
Physical activity in the leisure-time and commuting domains together, of duration 200 minutes/week, was associated with normal hs-CRP values.
Full text:
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Index:
LILACS (Americas)
Main subject:
C-Reactive Protein
/
Exercise
Type of study:
Diagnostic study
/
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicine
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
2020
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Escola Bahiana de Medicina e Saúde Pública/BR
/
Fundação Oswaldo Cruz/BR
/
Universidade Federal da Bahia/BR
/
Universidade Federal do Espirito Santo/BR
/
Universidade de São Paulo/BR
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