A brief-review of the risk factors for covid-19 severity
Rev. saúde pública (Online)
;
54: 60, 2020. tab
Article
in English
| LILACS, BBO
| ID: biblio-1101877
ABSTRACT
ABSTRACT The World Health Organization has emphasized that one of the most important questions to address regarding the covid-19 pandemic is to understand risk factors for disease severity. We conducted a brief review that synthesizes the available evidence and provides a judgment on the consistency of the association between risk factors and a composite end-point of severe-fatal covid-19. Additionally, we also conducted a comparability analysis of risk factors across 17 studies. We found evidence supporting a total of 60 predictors for disease severity, of which seven were deemed of high consistency, 40 of medium and 13 of low. Among the factors with high consistency of association, we found age, C-reactive protein, D-dimer, albumin, body temperature, SOFA score and diabetes. The results suggest that diabetes might be the most consistent comorbidity predicting disease severity and that future research should carefully consider the comparability of reporting cases, factors, and outcomes along the different stages of the natural history of covid-19.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Pneumonia, Viral
/
Severity of Illness Index
/
Coronavirus Infections
/
Betacoronavirus
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Rev. saúde pública (Online)
Journal subject:
Sa£de P£blica
Year:
2020
Type:
Article
Affiliation country:
Australia
Institution/Affiliation country:
Queensland University of Technology/AU
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