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Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections
Sabino, Sebastiana Silva; Lima, Caio Augusto de; Machado, Luiz Gustavo; Campos, Paola Amaral de; Fontes, Astrídia Marília de Souza; Gontijo-Filho, Paulo Pinto; Ribas, Rosineide Marques.
  • Sabino, Sebastiana Silva; Universidade Federal de Uberlândia. Faculdade de Medicina. Uberlândia. BR
  • Lima, Caio Augusto de; Universidade Federal de Uberlândia. Faculdade de Medicina. Uberlândia. BR
  • Machado, Luiz Gustavo; Universidade Federal de Uberlândia. Instituto de Ciências Biomédicas. Uberlândia. BR
  • Campos, Paola Amaral de; Universidade Federal de Uberlândia. Instituto de Ciências Biomédicas. Uberlândia. BR
  • Fontes, Astrídia Marília de Souza; Universidade Federal de Uberlândia. Faculdade de Medicina. Uberlândia. BR
  • Gontijo-Filho, Paulo Pinto; Universidade Federal de Uberlândia. Faculdade de Medicina. Uberlândia. BR
  • Ribas, Rosineide Marques; Universidade Federal de Uberlândia. Faculdade de Medicina. Uberlândia. BR
Rev. Soc. Bras. Med. Trop ; 53: e20190106, 2020. tab
Article in English | SES-SP, ColecionaSUS, LILACS | ID: biblio-1136811
ABSTRACT
Abstract

INTRODUCTION:

The present study aimed to determine the incidence of health care-associated infections (HCAIs) and identify the main resistant microorganisms in intensive care unit (ICU) patients in a Brazilian university hospital.

METHODS:

A retrospective cohort study was conducted in a Brazilian teaching hospital between 2012 and 2014.

RESULTS:

Overall, 81.2% of the infections were acquired in the ICU. The most common resistant pathogenic phenotypes in all-site and bloodstream infections were oxacillin-resistant coagulase-negative staphylococci and carbapenem-resistant Acinetobacter spp. (89.9% and 87.4%; 80.6% and 70.0%), respectively.

CONCLUSIONS:

There is an urgent need to focus on HCAIs in ICUs in Brazil.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Bacteremia / Drug Resistance, Bacterial / Gram-Negative Bacteria / Gram-Positive Bacteria / Anti-Bacterial Agents Type of study: Incidence study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Rev. Soc. Bras. Med. Trop Year: 2020 Type: Article Institution/Affiliation country: Universidade Federal de Uberlândia/BR

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Full text: Available Index: LILACS (Americas) Main subject: Bacteremia / Drug Resistance, Bacterial / Gram-Negative Bacteria / Gram-Positive Bacteria / Anti-Bacterial Agents Type of study: Incidence study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Rev. Soc. Bras. Med. Trop Year: 2020 Type: Article Institution/Affiliation country: Universidade Federal de Uberlândia/BR