Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores / Association between cognitive impairment and depression in Chilean older adults
Rev. méd. Chile
; 148(7): 947-955, jul. 2020. tab, graf
Article
in Es
| LILACS
| ID: biblio-1139396
Responsible library:
CL1.1
ABSTRACT
Background:
Depression has been previously associated with cognitive impairment in high income country populations. However, its association in the Chilean population has not been investigated.Aim:
To investigate the association between depression and cognitive impairment. Material andMethods:
Data from 1384 Chilean adults aged > 60 years, participating in the National Health Survey 2009-2010 was analyzed. Cognitive impairment was assessed using the Mini Mental Examination score. The medical diagnosis of depression was self-reported. The association between depression and cognitive impairment was assessed using a logistic regression.Results:
Depression was positively associated with cognitive impairment. However, the magnitude of the association was higher in men (Odds ratio (OR) = 4.02 [95% confidence intervals (CI) 1.44; 6.61], p < 0.01]) than in women (OR = 2.23 [95%CI 1.03; 3.43], p = 0.04). Older adults who were diagnosed for the first time with depression after 65 years of age, showed a stronger association with cognitive impairment (OR = 6.65 [95% CI 2.39; 10.9], p < 0.01) than those diagnosed before 55 years.Conclusions:
Our study confirms the association between depression and cognitive impairment. Further research is needed to elucidate the nature and potential mechanisms that link depression with cognitive impairment.Key words
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Index:
LILACS
Main subject:
Depression
/
Cognitive Dysfunction
Type of study:
Diagnostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
America do sul
/
Chile
Language:
Es
Journal:
Rev. méd. Chile
Journal subject:
MEDICINA
Year:
2020
Type:
Article