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The Clinical Course of Takotsubo Syndrome Diagnosed According to the InterTAK Criteria
Fundão, Nelson Henrique Fantin; Ribeiro, Henrique Barbosa; Campos, Carlos de Magalhães; Seleme, Vinicius Bocchino; Soeiro, Alexandre de Matos; Vieira, Marcelo Luiz Campos; Mathias Jr, Wilson; Hajjar, Ludhmilla Abraão; Ribeiro, Expedito E; Kalil Filho, Roberto.
  • Fundão, Nelson Henrique Fantin; Universidade de São Paulo. Instituto do Coração. São Paulo. BR
  • Ribeiro, Henrique Barbosa; Universidade de São Paulo. Instituto do Coração. São Paulo. BR
  • Campos, Carlos de Magalhães; Universidade de São Paulo. Instituto do Coração. São Paulo. BR
  • Seleme, Vinicius Bocchino; Universidade de São Paulo. Instituto do Coração. São Paulo. BR
  • Soeiro, Alexandre de Matos; Universidade de São Paulo. Instituto do Coração. São Paulo. BR
  • Vieira, Marcelo Luiz Campos; Universidade de São Paulo. Instituto do Coração. São Paulo. BR
  • Mathias Jr, Wilson; Universidade de São Paulo. Instituto do Coração. São Paulo. BR
  • Hajjar, Ludhmilla Abraão; Universidade de São Paulo. Instituto do Coração. São Paulo. BR
  • Ribeiro, Expedito E; Universidade de São Paulo. Instituto do Coração. São Paulo. BR
  • Kalil Filho, Roberto; Universidade de São Paulo. Instituto do Coração. São Paulo. BR
Int. j. cardiovasc. sci. (Impr.) ; 33(6): 637-647, Nov.-Dec. 2020. tab, graf
Article in English | LILACS | ID: biblio-1143106
ABSTRACT
Abstract Background There has been an increase in the number of cases of Takotsubo syndrome (TTS) and of scientific publications on the theme over the last years. However, little is known about the status of this disease in Brazilian hospitals. Objective To assess mortality and major adverse cardiovascular events (MACE) during hospitalization and follow-up of TTS patients seen in a tertiary hospital in Brazil. Methods This was a retrospective, observational study on 48 patients. Clinical data, signs and symptoms, complementary tests, MACE and all-cause mortality were assessed on admission and during follow-up. Kaplan-Meier curves were used for analysis of all-cause mortality and risk for MACE at median follow-up. The 95% confidence interval was also calculated for a significance level of 5%. Results Mean age of patients was 71 years (SD±13 years), and most patients were women (n=41; 85.4%). During hospitalization, four patients (8.3%) died and five (10.4%) developed MACE. At median follow-up of 354.5 days (IQR of 81.5-896.5 days), the risk of all-cause mortality and MACE was 11.1% (95% CI= 1.8-20.3%) and 12.7% (95% CI= 3.3-22.3%), respectively. Conclusion TTS was associated with high morbidity and mortality rates in a tertiary hospital in Brazil, which were comparable to those observed in acute coronary syndrome. Therefore, the severity of TTS should not be underestimated, and new therapeutic strategies are required. Int J Cardiovasc Sci. 2020; [online].ahead print, PP.0-0
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Full text: Available Index: LILACS (Americas) Main subject: Takotsubo Cardiomyopathy Type of study: Diagnostic study / Observational study / Risk factors Limits: Aged / Aged80 / Female / Humans / Male Language: English Journal: Int. j. cardiovasc. sci. (Impr.) Journal subject: Cardiology Year: 2020 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Takotsubo Cardiomyopathy Type of study: Diagnostic study / Observational study / Risk factors Limits: Aged / Aged80 / Female / Humans / Male Language: English Journal: Int. j. cardiovasc. sci. (Impr.) Journal subject: Cardiology Year: 2020 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de São Paulo/BR