Molecular epidemiology of Mycobacterium tuberculosis in Brazil before the whole genome sequencing era: a literature review
Mem. Inst. Oswaldo Cruz
;
116: e200517, 2021. tab, graf
Article
in English
| LILACS
| ID: biblio-1154877
ABSTRACT
Molecular-typing can help in unraveling epidemiological scenarios and improvement for disease control strategies. A literature review of Mycobacterium tuberculosis transmission in Brazil through genotyping on 56 studies published from 1996-2019 was performed. The clustering rate for mycobacterial interspersed repetitive units - variable tandem repeats (MIRU-VNTR) of 1,613 isolates were 73%, 33% and 28% based on 12, 15 and 24-loci, respectively; while for RFLP-IS6110 were 84% among prison population in Rio de Janeiro, 69% among multidrug-resistant isolates in Rio Grande do Sul, and 56.2% in general population in São Paulo. These findings could improve tuberculosis (TB) surveillance and set up a solid basis to build a database of Mycobacterium genomes.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Polymorphism, Restriction Fragment Length
/
Minisatellite Repeats
/
Mycobacterium tuberculosis
Type of study:
Screening study
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2021
Type:
Article
Affiliation country:
Brazil
/
France
/
India
Institution/Affiliation country:
Coordenação Geral de Vigilância das Doenças de Transmissão Respiratória de Condições Crônicas/BR
/
Fundação Oswaldo Cruz-Fiocruz/BR
/
Instituto Adolfo Lutz/BR
/
Instituto Evandro Chagas/BR
/
International Institute of Information Technology/IN
/
Secretaria Estadual de Saúde do Rio Grande do Sul/BR
/
Universidade Federal de São Paulo/BR
/
Universidade Federal do Rio Grande do Sul/BR
/
Universidade Federal do Rio de Janeiro/BR
/
Universidade de São Paulo/BR
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