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Larger Chondral Lesions Treated with Collagen Membrane - Matrix-Induced Autologous Chondrogenesis - Show Larger Increase in Clinical Scores / Lesões condrais maiores tratadas com uso de membrana de colágeno - condrogênese autóloga induzida por matriz - apresentam maior aumento nos escores clínicos
Miyahira, Mateus Kenji Christo; Department of Orthopedics and TraumatologyNovaretti, João Victor; Department of Orthopedics and TraumatologyAstur, Diego Costa; Kaleka, Camila Cohen; Amaro, Joicemar Tarouco; Department of Orthopedics and TraumatologyCohen, Moisés.
  • Miyahira, Mateus Kenji Christo; Cohen Institute of Orthopedics, Reabilitation and Sports Medicine. São Paulo. BR
  • Department of Orthopedics and TraumatologyNovaretti, João Victor; Universidade Federal de São Paulo. Escola Paulista de Medicina. Department of Orthopedics and TraumatologyNovaretti, João Victor. São Paulo. BR
  • Department of Orthopedics and TraumatologyAstur, Diego Costa; Universidade Federal de São Paulo. Escola Paulista de Medicina. Department of Orthopedics and TraumatologyAstur, Diego Costa. São Paulo. BR
  • Kaleka, Camila Cohen; Cohen Institute of Orthopedics, Reabilitation and Sports Medicine. São Paulo. BR
  • Amaro, Joicemar Tarouco; Cohen Institute of Orthopedics, Reabilitation and Sports Medicine. São Paulo. BR
  • Department of Orthopedics and TraumatologyCohen, Moisés; Universidade Federal de São Paulo. Escola Paulista de Medicina. Department of Orthopedics and TraumatologyCohen, Moisés. São Paulo. BR
Rev. bras. ortop ; 56(3): 333-339, May-June 2021. tab, graf
Article in English | LILACS | ID: biblio-1288682
ABSTRACT
Abstract Objective To evaluate clinically and radiologically the results of the treatment of chondral lesions using collagen membrane - autologous matrix-induced chondrogenesis (AMIC). Methods This is a series of observational cases, in which 15 patients undergoing AMIC were analyzed. The clinical evaluation was made by comparing the Lysholm and International Knee Document Commitee (IKDC) scores in the pre- and postoperative period of 12 months, and radiological evaluation using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score in the same postoperative period. Results The mean age of the patients was 39.2 years old, and the mean size of the chondral lesions was 1.55cm2. There was a significant improvement in clinical scores, with a mean increase of 24.6 points on Lysholm and of 24.3 on IKDC after 12 months. In the radiological evaluation, MOCART had a mean of 65 points. It was observed that the larger the size of the lesion, the greater the improvement in scores. Conclusion Evaluating subjective clinical scores, the treatment of chondral lesions with the collagen membrane showed good results, as well as the evaluation of MOCART, with greater benefit in larger lesions.
RESUMO
Resumo Objetivo Avaliar clínica e radiologicamente os resultados do tratamento das lesões condrais com a membrana de colágeno - condrogênese autóloga induzida por matriz. Métodos Trata-se de uma série de casos observacional, na qual foram analisados 15 pacientes submetidos a condrogênese autóloga induzida por matriz. A avaliação clínica foi feita comparando os escores de Lysholm e International Knee Document Commitee (IKDC, na sigla em inglês) no pré- e pós-operatório de 12 meses, e avaliação radiológica através do escore de Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART, na sigla em inglês) no mesmo período de pós-operatório. Resultados A média de idade dos pacientes foi 39,2 anos, e a média do tamanho das lesões condrais foi de 1,55cm2. Houve uma melhora significativa nos escores clínicos, com média de aumento de 24,6 pontos no Lysholm e de 24,3 no IKDC, após 12 meses. Na avaliação radiológica, o MOCART teve média de 65 pontos. Observou-se que quanto maior o tamanho da lesão, maior foi a melhora nos escores. Conclusão Avaliando escores clínicos subjetivos, o tratamento das lesões condrais com a membrana de colágeno mostrou bons resultados, assim como a avaliação de MOCART, com maior benefício em lesões maiores.
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Full text: Available Index: LILACS (Americas) Main subject: Postoperative Period / Magnetic Resonance Spectroscopy / Cartilage, Articular / Collagen / Chondrogenesis / Knee Injuries Limits: Adolescent / Adult / Female / Humans / Male Language: English Journal: Rev. bras. ortop Journal subject: Orthopedics Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: Cohen Institute of Orthopedics, Reabilitation and Sports Medicine/BR / Universidade Federal de São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Postoperative Period / Magnetic Resonance Spectroscopy / Cartilage, Articular / Collagen / Chondrogenesis / Knee Injuries Limits: Adolescent / Adult / Female / Humans / Male Language: English Journal: Rev. bras. ortop Journal subject: Orthopedics Year: 2021 Type: Article Affiliation country: Brazil Institution/Affiliation country: Cohen Institute of Orthopedics, Reabilitation and Sports Medicine/BR / Universidade Federal de São Paulo/BR