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Mucosal Schwann cell hamartoma of the gallbladder
Ismael, Farhan; Khawar, Sidrah; Hamza, Ameer.
  • Ismael, Farhan; Dow University of Health Sciences Karachi. Department of Pathology. Karachi. PK
  • Khawar, Sidrah; University of Kansas. University of Kansas Medical Center. Department of Pathology. Kansas City. US
  • Hamza, Ameer; University of Kansas. University of Kansas Medical Center. Department of Pathology. Kansas City. US
Autops. Case Rep ; 11: e2021338, 2021. tab, graf
Article in English | LILACS | ID: biblio-1345357
ABSTRACT
Mucosal Schwann cell hamartoma (MSCH) is a rare benign neurogenic tumor characterized by pure S100p positive spindle cell proliferation. Most cases occur in the distal colon. Involvement of the gall bladder is exceedingly rare. There have been no reports of recurrence or a syndromic association with MSCH. Herein, we describe a case of MSCH of the gallbladder in a 55-year-old female patient with prior history of gastrointestinal neurofibromas who presented with abdominal pain. MR imaging revealed choledocholithiasis, gallbladder thickening, and marked biliary and pancreatic ductal dilation. The patient subsequently underwent cholecystectomy with choledochoduodenostomy. Histologic evaluation of the gallbladder showed diffuse expansion of the mucosa with S100p positive cells with spindly nuclei and indistinct cytoplasmic borders and diagnosis of MSCH of the gallbladder was rendered.
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Full text: Available Index: LILACS (Americas) Main subject: Schwann Cells / Gallbladder Neoplasms / Hamartoma / Neurofibroma Limits: Female / Humans Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2021 Type: Article Affiliation country: Pakistan / United States Institution/Affiliation country: Dow University of Health Sciences Karachi/PK / University of Kansas/US

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Full text: Available Index: LILACS (Americas) Main subject: Schwann Cells / Gallbladder Neoplasms / Hamartoma / Neurofibroma Limits: Female / Humans Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2021 Type: Article Affiliation country: Pakistan / United States Institution/Affiliation country: Dow University of Health Sciences Karachi/PK / University of Kansas/US