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Spectral analysis and Antibacterial activity of the bioactive principles of Sargassum tenerrimum J. Agardh collected from the Red sea, Jazan, Kingdom of Saudi Arabia / Análise espectral e atividade antibacteriana dos princípios bioativos de Sargassum tenerrimum J. Agardh coletados no mar Vermelho, Jazan, Reino da Arábia Saudita
Albratty, M; Alhazmi, H A; Meraya, A M; Najmi, A; Alam, M S; Rehman, Z; Moni, S S.
  • Albratty, M; Jazan University. College of Pharmacy. Department of Pharmaceutical Chemistry. Jazan. SA
  • Alhazmi, H A; Jazan University. College of Pharmacy. Department of Pharmaceutical Chemistry. Jazan. SA
  • Meraya, A M; azan University. College of Pharmacy. Department of Clinical Pharmacy. Jazan. SA
  • Najmi, A; Jazan University. College of Pharmacy. Department of Pharmaceutical Chemistry. Jazan. SA
  • Alam, M S; Jazan University. College of Pharmacy. Department of Pharmaceutical Chemistry. Jazan. SA
  • Rehman, Z; Jazan University. College of Pharmacy. Department of Pharmaceutical Chemistry. Jazan. SA
  • Moni, S S; Jazan University. College of Pharmacy. Department of Pharmaceutics. Jazan. SA
Braz. j. biol ; 83: e249536, 2023. tab, graf
Article in English | LILACS, VETINDEX | ID: biblio-1345531
ABSTRACT
Abstract Seaweeds are a major marine resource that can be explored to develop novel pharmaceutical molecules. The present study showed the presence of unique bioactive components in the petroleum ether extract (PEE) and methanolic extract (ME) of Sargassum tenerrimum. The gas chromatography-mass spectrometry analysis suggested that the PEE of S. tenerrimum contained antibacterial biomolecules hexadecanoic acid, methyl ester, 17-pentatriacontene, dasycarpidan-1-methanol, and acetate (ester). However, the ME of S. tenerrimum exhibited better antibacterial effect than the PEE due to the presence of the bioactive compounds 1,2-benzenedicarboxylic acid, diisooctyl ester, tetratetracontane, 1-docosene, 1,2-benzenediol, and benzoic acid. Thus, promising antibacterial molecules can be isolated from S. tenerrimum for better therapeutic use.
RESUMO
Resumo As algas marinhas são um importante recurso marinho que pode ser explorado para desenvolver novas moléculas farmacêuticas. O presente estudo mostrou a presença de componentes bioativos únicos no extrato etéreo de petróleo (PEE) e no extrato metanólico (ME) de Sargassum tenerrimum. A análise por cromatografia gasosa-espectrometria de massa sugeriu que o PEE de S. tenerrimum continha biomoléculas antibacterianas ácido hexadecanoico, éster metílico, 17-pentatriaconteno, dasycarpidan-1-metanol e acetato (éster). Entretanto, o ME de S. tenerrimum exibiu melhor efeito antibacteriano do que o PEE devido à presença dos compostos bioativos ácido 1,2-benzenodicarboxílico, éster diisooctil, tetratetracontano, 1-docosene, 1,2-benzoenodiol e ácido benzoico. Assim, moléculas antibacterianas promissoras podem ser isoladas de S. tenerrimum para melhor uso terapêutico.
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Full text: Available Index: LILACS (Americas) Main subject: Sargassum Country/Region as subject: Asia Language: English Journal: Braz. j. biol Year: 2023 Type: Article Institution/Affiliation country: Jazan University/SA

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Full text: Available Index: LILACS (Americas) Main subject: Sargassum Country/Region as subject: Asia Language: English Journal: Braz. j. biol Year: 2023 Type: Article Institution/Affiliation country: Jazan University/SA