Effects of Physical Exercise on Lipid and Inflammatory Profile of Women Using Combined Oral Contraceptive: A Cross-Over Study
Int. j. cardiovasc. sci. (Impr.)
;
35(4): 500-510, July-Aug. 2022. tab, graf
Article
in English
| LILACS
| ID: biblio-1385267
ABSTRACT
Abstract Background:
The use of combined oral contraceptives (COC) is a risk factor for atherosclerotic disease, and physical exercise can minimize this condition.Objective:
To verify if high intensity interval training (HIIT) promotes changes in the lipid and inflammatory profile of women using COC.Methods:
Sequential crossover study with women aged 20-30 years, classified as irregularly active by the international physical activity questionnaire (IPAQ), when using COC. A physical-clinical assessment was performed with anthropometric measurements, VO2max, and analysis of lipid and inflammatory profile. Participants were divided into 2 groups the initial intervention group (GII), which began practicing HIIT for 2 months, and the posterior intervention group (GIP), which remained inactive for the same period. The GII and GIP would then alternate their conditions. The collected data was divided into Initial moment (IM), post-exercise moment (PEM) and post-inactivity (PIM). The statistical analyses were performed using the Statistical Package for the Social Sciences, adopting a significance level of p <0.05 .Results:
Twelve women were evaluated. After crossing the GII and GIP data, there was a difference in the C-reactive protein values between the IM of 4 (1.6-6.3 mg/dL) vs. PEM 2 (1.5-5 mg/dL); as well as between the PEM vs. the PIM= 4 (1.5-5.8 mg/dL), with a p -value = 0.04 in the comparisons. There was no change between the "moments" of the lipid profile, although it was possible to notice a reduction in resting HR and an increase in indirect VO2max.Conclusion:
The HIIT program was able to reduce the inflammatory profile, but it did not alter the lipid profile of irregularly active women using COC.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Contraceptives, Oral, Combined
/
Atherosclerosis
/
High-Intensity Interval Training
Type of study:
Controlled clinical trial
/
Etiology study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Int. j. cardiovasc. sci. (Impr.)
Journal subject:
Cardiology
Year:
2022
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Escola Bahiana de Medicina e Saúde Pública/BR
/
Hospital Bom Jesus/BR
/
Instituto Gonçalo Moniz (Fiocruz Bahia)/BR
Similar
MEDLINE
...
LILACS
LIS