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Aportes de la tomografía por emisión de positrones con 18F-fluorodesoxiglucosa/tomografía computada en el diagnóstico de compromiso extramedular por mieloma múltiple en Uruguay / 18F-fluorodesoxyglucose positron emission tomography/computed tomography in extramedullary multiple myeloma
Lissarrague, Eugenia; Fregeiro, María Sol; Binstok, Yemile; Barla, Camila; Cavani, Manuel; Frachia, Felipe; Ranero, Sabrina; Servente, Liliana; Riva, Eloísa.
  • Lissarrague, Eugenia; Universidad de la República. Montevideo. UY
  • Fregeiro, María Sol; Universidad de la República. Montevideo. UY
  • Binstok, Yemile; Universidad de la República. Montevideo. UY
  • Barla, Camila; Universidad de la República. Montevideo. UY
  • Cavani, Manuel; Universidad de la República. Montevideo. UY
  • Frachia, Felipe; Universidad de la República. Montevideo. UY
  • Ranero, Sabrina; Universidad de la República. Hospital de Clínicas Dr. Manuel Quíntela. Montevideo. UY
  • Servente, Liliana; Universidad de la República. Hospital de Clínicas Dr. Manuel Quintela. Departamento Clínico de Imagenología. Montevideo. UY
  • Riva, Eloísa; Universidad de la República. Hospital de Clínicas Dr. Manuel Quíntela. Montevideo. UY
Rev. méd. Chile ; 150(2): 199-205, feb. 2022. tab
Article in Spanish | LILACS | ID: biblio-1389644
ABSTRACT

BACKGROUND:

18F-fluorodesoxyglucose positron emission tomography/ computed tomography (PET-CT) has a high sensitivity and specificity to detect medullary and extramedullary lesions in multiple myeloma (MM).

AIM:

To describe the findings of PET-CT in extramedullary multiple myeloma (EMM) at diagnosis and at relapse, and correlate its results with clinical variables, response to treatment and survival. MATERIALS AND

METHODS:

Review of medical records and PET-CT reports of 39 patients with multiple myeloma (MM) who had at least one PET-CT study, treated between January 1, 2015, and January 1, 2019 at a clinical hospital.

RESULTS:

The Standard Uptake Values for each hypermetabolic lesion were not described in PET-CT reports. Fifteen patients had an EMM and in eight, without a previous clinical suspicion, PET-TC lead to the diagnosis. The mortality rate in the 39 patients with MM was 46%. Sixty seven percent of deaths occurred in patients with EMM.

CONCLUSIONS:

PET-TC was useful to diagnose EMM. However, a standardization in PETCT reports would be required to unify criteria. As previously reported, EMM had a greater aggressiveness and lower survival.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Positron Emission Tomography Computed Tomography / Multiple Myeloma Type of study: Diagnostic study Limits: Humans Country/Region as subject: South America / Uruguay Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2022 Type: Article Affiliation country: Uruguay Institution/Affiliation country: Universidad de la República/UY

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Full text: Available Index: LILACS (Americas) Main subject: Positron Emission Tomography Computed Tomography / Multiple Myeloma Type of study: Diagnostic study Limits: Humans Country/Region as subject: South America / Uruguay Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2022 Type: Article Affiliation country: Uruguay Institution/Affiliation country: Universidad de la República/UY