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Prevalence and seroprevalence of COVID-19 in suspected malaria during the second wave in Yaounde, Cameroon
Voundi-Voundi, Esther; Mene Tenku, Isabelle-Claire; Voundi-Voundi, Junior; Ngogang, Marie Paule; Doumou A Mvomo, Nadège Lylian; Medi-Sike, Christiane; Toukam, Michel.
  • Voundi-Voundi, Esther; Department of Microbiology, Parasitology, Hematology and infectious diseases, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I. Yaoundé. CM
  • Mene Tenku, Isabelle-Claire; Jordan Medical Services, Cameroon. Yaoundé. CM
  • Voundi-Voundi, Junior; Ministry of Public Health, Cameroon. Yaoundé. CM
  • Ngogang, Marie Paule; Department of Microbiology, Parasitology, Hematology and infectious diseases, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I. Yaoundé. CM
  • Doumou A Mvomo, Nadège Lylian; Jordan Medical Services, Cameroon. Yaoundé. CM
  • Medi-Sike, Christiane; Department of Microbiology, Parasitology, Hematology and infectious diseases, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I. Yaoundé. CM
  • Toukam, Michel; Department of Microbiology, Parasitology, Hematology and infectious diseases, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Cameroon. Yaoundé. CM
Health sci. dis ; 24(2 Suppl 1): 26-30, 2023. figures, tables
Article in French | AIM | ID: biblio-1416528
ABSTRACT
Background. The COVID-19 pandemic has added an additional burden in countries with already fragile health systems. Our objective was to determine the prevalence and seroprevalence of COVID-19 in suspected malaria during the second wave in Yaounde. Methods. A descriptive cross-sectional study was conducted at the Jordan Medical Services for 8 weeks from April 19 to June 13, 2021, i.e., during the second wave in Cameroon. For the 86 patients with suspected malaria, nasopharyngeal and blood samples were taken for SARS-CoV-2 antigen and anti-SARS-CoV-2 IgG and IgM using the STANDARD TM Q COVID-19 Ag kit from SD BIOSENSOR, Korea, 2020 and Standard TM Q COVID 19 Ac IgG/IgM kit from SD BIOSENSOR, Korea, 2020 respectively. Confirmation of malaria was done by microscopic examination of stained blood smears. Results. Malaria was confirmed in 20.9% (18) of cases. The prevalences of COVID-19 and COVID-19/malaria co-infection were 8.1% and 0.9% respectively. Of the 25.6% (54) of patients with anti-COVID-19 IgM, no positive microscopic cases were found. On the other hand, a little more than half of the patients had IgG antibodies against COVID-19 whether they had a positive thick drop or not (56.0% (42/75) and 52.2% (71/136) respectively). Conclusion. In case of suspicion of malaria in a malaria area, it seems important to consider COVID-19 as a differential diagnosis.
Introduction. La pandémie de la COVID-19 a ajouté un fardeau supplémentaire dans les pays aux systèmes de santé déjà fragiles. Objectif déterminer la prévalence et la séroprévalence de la COVID-19 en cas de suspicion du paludisme au cours de la deuxième vagueà Yaoundé. Méthodologie. Une étude transversale descriptive a été menée au Centre Médical le Jourdain pendant 8 semaines du 19 Avril au 13 Juin 2021 soit durant la deuxième vague au Cameroun. Pour les 86 patients avec suspicion de paludisme, des prélèvements nasopharyngé et sanguins ont été réalisés pour la recherche d'antigène du SRAS- CoV 2 et des IgG et IgM anti-SARS-CoV-2 grâce aux kits STANDARDTM Q COVID-19 Ag de SD BIOSENSOR, Corée, 2020 et StandardTM Q COVID 19 Ac IgG/IgM de SD BIOSENSOR, Corée, 2020 respectivement. La confirmation du paludisme a été faite grâce à l'examen microscopique des étalements de sang colorés. Résultats. Le paludisme était confirmé dans 20,9% (18) des cas. Les prévalences de la COVID-19 et de la coïnfection COVID19/Paludisme étaient de 8,1% et de 0,9% respectivement. Sur les 25,6% (54) des patients avec des IgM anti-COVID-19, aucun cas de microscopie positive n'a été retrouvé. Par ailleurs un peu plus de la moitié des patients avaient des anticorps IgG anti-COVID-19 qu'ils aient une goutte épaisse positive ou pas soit 56,0% (42/75) et 52,2% (71/136) respectivement. Conclusion. En cas de suspicion du paludisme en zone impaludée, il parait non négligeable de considérer la COVID-19 comme un diagnostic différentiel.

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Full text: Available Index: AIM (Africa) Main subject: Signs and Symptoms / COVID-19 / Malaria Type of study: Observational study / Prevalence study / Risk factors Limits: Female / Humans / Male Language: French Journal: Health sci. dis Year: 2023 Type: Article Institution/Affiliation country: Department of Microbiology, Parasitology, Hematology and infectious diseases, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I/CM / Department of Microbiology, Parasitology, Hematology and infectious diseases, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Cameroon/CM / Jordan Medical Services, Cameroon/CM / Ministry of Public Health, Cameroon/CM

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Full text: Available Index: AIM (Africa) Main subject: Signs and Symptoms / COVID-19 / Malaria Type of study: Observational study / Prevalence study / Risk factors Limits: Female / Humans / Male Language: French Journal: Health sci. dis Year: 2023 Type: Article Institution/Affiliation country: Department of Microbiology, Parasitology, Hematology and infectious diseases, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I/CM / Department of Microbiology, Parasitology, Hematology and infectious diseases, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Cameroon/CM / Jordan Medical Services, Cameroon/CM / Ministry of Public Health, Cameroon/CM