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Malignant melanoma with synchronous thyroid metastases: case report and literature review
Costa, Maria Manuel; Belo, Sandra; Capela-Costa, João; Costa, Jennifer; Carvalho, Davide.
  • Costa, Maria Manuel; Faculty of Medicine University of Porto. Centro Hospitalar São João. Department of Endocrinology, Diabetes and Metabolism. Porto. PT
  • Belo, Sandra; Faculty of Medicine University of Porto. Centro Hospitalar São João. Department of Endocrinology, Diabetes and Metabolism. Porto. PT
  • Capela-Costa, João; Faculty of Medicine University of Porto. Centro Hospitalar São João. Department of Endocrinology, Diabetes and Metabolism. Porto. PT
  • Costa, Jennifer; Faculty of Medicine University of Porto. Centro Hospitalar São João. Department of Endocrinology, Diabetes and Metabolism. Porto. PT
  • Carvalho, Davide; Faculty of Medicine University of Porto. Centro Hospitalar São João. Department of Endocrinology, Diabetes and Metabolism. Porto. PT
Arch. endocrinol. metab. (Online) ; 61(2): 193-197, Mar.-Apr. 2017. graf
Article in English | LILACS | ID: biblio-838439
ABSTRACT
SUMMARY Thyroid metastases are rare in clinical practice. We describe the case of an 85-year-old woman who was referred to our department due to a multinodular goiter with compressive symptoms and subclinical hyperthyroidism. The patient was also undergoing evaluation for a polyp in her left nasal cavity, which was then diagnosed as a malignant melanoma of the nasal mucosa. A thoracoabdominal magnetic resonance imaging obtained for cancer staging revealed a > 50% tracheal obstruction caused by the goiter. The patient underwent simultaneous total thyroidectomy and melanoma excision. Histological analysis of the thyroid showed the presence of multiple metastatic foci from the melanoma. Due to the patient’s age, a decision was made to maintain her under surveillance and administer palliative treatment if necessary. Although metastases to the thyroid are rare, they should be considered in the differential diagnosis of thyroid lesions in patients with a known primary tumor. The thyroidectomy, performed in this patient’s case, allowed the diagnosis of the metastases and relief of compressive symptoms caused by the goiter.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Thyroid Neoplasms / Nose Neoplasms / Melanoma Type of study: Prognostic study Limits: Aged / Aged80 / Female / Humans Language: English Journal: Arch. endocrinol. metab. (Online) Journal subject: Endocrinology / Metabolism Year: 2017 Type: Article Affiliation country: Portugal Institution/Affiliation country: Faculty of Medicine University of Porto/PT

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Full text: Available Index: LILACS (Americas) Main subject: Thyroid Neoplasms / Nose Neoplasms / Melanoma Type of study: Prognostic study Limits: Aged / Aged80 / Female / Humans Language: English Journal: Arch. endocrinol. metab. (Online) Journal subject: Endocrinology / Metabolism Year: 2017 Type: Article Affiliation country: Portugal Institution/Affiliation country: Faculty of Medicine University of Porto/PT