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Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report
de Fátima Borges, Maria; Lara, Beatriz Hallal Jorge; Tomé, Janaíne Machado; de Araújo, Leopoldo Prezia; Bugiga, Flávio Cesar Lucas; Sousa, Júlio Cláudio; Soares, Jacqueline Mendes Fonseca; Dezena, Roberto Alexandre; Ferreira, Beatriz Pires.
Affiliation
  • de Fátima Borges, Maria; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Lara, Beatriz Hallal Jorge; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Tomé, Janaíne Machado; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • de Araújo, Leopoldo Prezia; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Bugiga, Flávio Cesar Lucas; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Sousa, Júlio Cláudio; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Soares, Jacqueline Mendes Fonseca; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Dezena, Roberto Alexandre; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Ferreira, Beatriz Pires; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
Clinics ; 72(4): 218-223, Apr. 2017. tab, graf
Article in En | LILACS | ID: biblio-840068
Responsible library: BR1.1
ABSTRACT

OBJECTIVE:

To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro.

METHODS:

Cross-sectional and retrospective study of thirty cases treated over a period of two decades.

RESULTS:

17 men (56.7%) aged 14-67 years and 13 women aged 14-86 years were analyzed. Twenty-one patients underwent transphenoidal surgery, whichwas associated with somatostatin receptor ligands in 11 patients (39.3%), somatostatin receptor ligands + radiotherapyin 5 patients (17.8%), radiotherapy in 3 patients (10.7%), and radiotherapy + somatostatin receptorligands + cabergoline in 1 patient (3.6%). Additionally, 2 patients underwent radiotherapy and surgeryalone. Six patients received somatostatin receptor ligands before surgery, and 2 were not treated due to refusal and death. Nine patients have died, and 20 are being followed; 13 (65%) have growth hormonelevels o1 ng/mL, and 11 have normal insulin-like growth factor 1 levels.

CONCLUSION:

The current treatment options enable patients seen in regional reference centers to achieve strict control parameters, which allows them to be treated close to their homes.
Subject(s)
Key words

Full text: 1 Index: LILACS Main subject: Acromegaly / Adenoma / Receptors, Somatostatin / Growth Hormone-Secreting Pituitary Adenoma Type of study: Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male Country/Region as subject: America do sul / Brasil Language: En Journal: Clinics Journal subject: MEDICINA Year: 2017 Type: Article

Full text: 1 Index: LILACS Main subject: Acromegaly / Adenoma / Receptors, Somatostatin / Growth Hormone-Secreting Pituitary Adenoma Type of study: Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male Country/Region as subject: America do sul / Brasil Language: En Journal: Clinics Journal subject: MEDICINA Year: 2017 Type: Article