Capsiate treatment in liver surgeries may compromise its recovery
Acta cir. bras
; 33(5): 439-445, May 2018. graf
Article
in En
| LILACS
| ID: biblio-949344
Responsible library:
BR1.1
ABSTRACT
Abstract Purpose:
To investigate the effects of capsiate treatment on hepatic hyperplasia in partially hepatectomized rats.Methods:
The animals were divided into a Capsiate group (CPH), a Capsiate Post-Partial Hepatectomy group (CPPH) and a Partial Hepatectomy Control group (PH). CPH and CPPH animals received 60 mg/kg/day Capsiate for 30 days. Next, the rats underwent partial hepatectomy. CPPH animals continued to receive treatment for 48 h after partial hepatectomy. Liver tissue and intracardiac blood samples were obtained 24 or 48 h after PH.Results:
Capsiate treatment interfered with hepatic parameters, reducing the number of mitoses and apoptosis and increasing blood ALT and alkaline phosphatase concentrations.Conclusion:
Capsiate treatment preceding hepatic surgery may compromise the initial period of postoperative recovery.Key words
Full text:
1
Index:
LILACS
Main subject:
Capsaicin
/
Hepatectomy
/
Liver
Limits:
Animals
Language:
En
Journal:
Acta cir. bras
Journal subject:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2018
Type:
Article