CD133 is not suitable marker for isolating melanoma stem cells from D10 cell line

Motahareh Rajabi, Fomeshi; Marzieh, Ebrahimi; Seyed Javad Mowla; Javad, Firouzi; Pardis, Khosravani

Motahareh Rajabi, Fomeshi; Marzieh, Ebrahimi; Seyed Javad Mowla; Javad, Firouzi; Pardis, Khosravani.

Cell Journal [Yakhteh]. 2016; 18 (1): 21-27

in English | IMEMR | ID: emr-178842

ABSTRACT

ABSTRACT

Objective:

Cutaneous melanoma is the most hazardous malignancy of skin cancer with a high mortality rate. It has been reported that cancer stem cells [CSCs] are responsible for malignancy in most of cancers including melanoma. The aim of this study is to compare two common methods for melanoma stem cell enriching; isolating based on the CD133 cell surface marker and spheroid cell culture

Subject(s)

Peptides; Antigens, CD; Melanoma; Homeodomain Proteins; Transcription Factors; Stem Cells; Cell Line; Spheroids, Cellular; Cells, Cultured

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Index: IMEMR (Eastern Mediterranean) Main subject: Peptides / Stem Cells / Transcription Factors / Antigens, CD / Cell Line / Cells, Cultured / Homeodomain Proteins / Spheroids, Cellular / Melanoma Language: English Journal: Cell J. [Yakhteh] Year: 2016

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