Cell Journal [Yakhteh]. 2016; 18 (2): 189-196
in English
| IMEMR
| ID: emr-183008
ABSTRACT
Objective:
Treatment and repair of neurodegenerative diseases such as brain tumors, spinal cord injuries, and functional disorders, including Alzheimer's disease, are challenging problems. A common treatment approach for such disorders involves the use of mesenchymal stem cells [MSCs] as an alternative cell source to replace injured cells. However, use of these cells in hosts may potentially cause adverse outcomes such as tumorigenesis and uncontrolled differentiation. In attempt to generate mesenchymal derived neural cells, we have infected MSCs with recombinant lentiviruses that expressed nerve growth factor [NGF] and assessed their neural lineage genes
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Cell J. [Yakhteh]
Year:
2016
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