Screening of Aerva javanica and Linum ustitatissimum for their antidiabetic and anti-oxidant activity

ABSTRACT

The present study investigates anti-diabetic and anti-oxidant potentials of the aerial parts of Aerva javanica and seeds of Linum ustitatissimum. Our results revealed that maximum antioxidant activity was found in hexane fractions of both plants. Linum ustitatissimum recorded maximum antioxidant value of 15.77mmol/L while Aerva javanica had antioxidant activity of 16.07mmol/L. Anti-diabetic activities were also evaluated using normal rats, induced diabetic [untreated] rats and treated diabetic rats. Aerva javanica revealed a significant potential in decreasing blood glucose level to 77.08mg/dl and body weight 76.30mg/kg while Linum ustitatissimum reduced blood glucose level to 84.20mg/dl and body weight 83.090mg/kg. From these results it can be concluded that both plants possesses antidiabetic and anti-oxidant activity