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In vitro differentiation of neural-like cells from human embryonic stem cells by a combination of dorsomorphin, XAV939, and A8301
Cell Journal [Yakhteh]. 2018; 19 (4): 545-551
in English | IMEMR | ID: emr-189844
ABSTRACT

Objective:

motor neuron differentiation from human embryonic stem cells [hESCs] is a goal of regenerative medicine to provide cell therapy as treatments for diseases that damage motor neurons. Most protocols lack adequate efficiency in generating functional motor neurons. However, small molecules present a new approach to overcome this challenge. The aim of this research is to replace morphogen factors with a cocktail of efficient, affordable small molecules for effective, low cost motor neuron differentiation
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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Cell J. [Yakhteh] Year: 2018

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Cell J. [Yakhteh] Year: 2018