Conditioned media derived from human adipose tissue mesenchymal stromal cells improves primary hepatocyte maintenance

ABSTRACT

Objective: Recent advances in cell therapy have encouraged researchers to provide an alternative for treatment and restoration of damaged liver through using hepatocytes. However, these cells quickly lose their functional capabilities in vitro. Here, we aim to use the secretome of mesenchymal stromal cells [MSCs] to improve in vitro maintenance conditions for hepatocytes