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Anacardic acid reduces acetylation of H4K12 in mouse Oocytes during vitrification
Cell Journal [Yakhteh]. 2019; 20 (4): 552-558
in English | IMEMR | ID: emr-199625
Responsible library: EMRO
ABSTRACT

Objective:

Over the last years, vitrification has been widely used for oocyte cryopreservation, in animals and humans; however, it frequently causes minor and major epigenetic modifications. The effect of oocyte vitrification on levels of acetylation of histone H4 at lysine 12 [AcH4K12], and histone acetyltransferase [Hat] expression, was previously assessed; however, little is known about the inhibition of Hat expression during oocyte vitrification. This study evaluated the effect of anacardic acid [AA] as a Hat inhibitor on vitrified mouse oocytes
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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Cell J. [Yakhteh] Year: 2019

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Cell J. [Yakhteh] Year: 2019