The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus
Mem. Inst. Oswaldo Cruz
; 88(3): 431-4, July-Sept. 1993. tab, graf
Article
in En
| LILACS
| ID: lil-148798
Responsible library:
BR1.1
ABSTRACT
The influence of the subminimal inhibitory concentrations (1/3 and 1/4 of the MIC) of penicillin on growth rate and on haemolysin production of a strain of group G Streptococcus was studied. It was shown that 1/3 of the MIC almost completely inhibited the bacterial growth, but it was not able to inhibit haemolysin activity in the culture supernate. The generation time of bacteria grown in 1/4 of the MIC was approximately twice longer than that of the control culture. In all cultures, the haemolysin, after being produced (or liberated), reached a peak and decreased to low levels, which could suggest that group G Streptococcus produces some end products of metabolism that are able to inhibit haemolysin activity
Full text:
1
Index:
LILACS
Main subject:
Penicillins
/
Streptococcus
/
Hemolysin Proteins
Language:
En
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
MEDICINA TROPICAL
/
PARASITOLOGIA
Year:
1993
Type:
Article