Clinical and microbiological characterization of KPC-producing Klebsiella pneumoniae infections in Brazil
Braz. j. infect. dis
; 15(1): 69-73, Jan.-Feb. 2011. tab
Article
in En
| LILACS
| ID: lil-576789
Responsible library:
BR1.1
ABSTRACT
In 2008 isolates of KPC-producing Klebsiella pneumoniae (KPC-KPN) were detected for the first time at Hospital Heliópolis, São Paulo, Brazil. The aim of this study was to characterize the clinical and microbiological outcomes of infections caused by KPC-KPN. A historical cohort of patients from whom KPC-KPN strains were isolated was performed. Isolates were identified as resistant to ertapenem by automated broth microdilution system and screened as carbapenemase producers by the modified Hodge test. The beta-lactamase resistance gene blaKPC was detected by PCR. The genetic relatedness of isolates was determined by PFGE. The study provides early clinical experience in treating KPC-KPN infections in a Brazilian tertiary center.
Key words
Full text:
1
Index:
LILACS
Main subject:
Bacterial Proteins
/
Beta-Lactamases
/
Klebsiella Infections
/
Klebsiella pneumoniae
/
Anti-Bacterial Agents
Type of study:
Prognostic_studies
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Braz. j. infect. dis
Journal subject:
DOENCAS TRANSMISSIVEIS
Year:
2011
Type:
Article