The protective effect of zinc on gastric ulceration caused by ethanol treatment
Braz. j. med. biol. res
; 22(1): 41-50, 1989. ilus
Article
in En
| LILACS
| ID: lil-67471
Responsible library:
BR26.1
ABSTRACT
1. The present study was undertaken in order to demonstrate the protective action of zinc ions on the gastric mucosa of rats submitted to the ulcerogenic effect of ethanol. 2. Aqueous solutions of zinc sulfate (20 mg/kg) and/or ethanol/water (11,v/v) (10ml/kg) were intragastrically administered to young adult rats. The fundus region of the stomach was submitted to scanning electron and light microscopy study. The control group received isotonic sodium sulfate by the same route. 3. The ulcerogenic action of ethanol was completely inhibited by intragastric pretreatment with zinc sulfate for 3 consecutive days. 4. The clinical use of zinc ions to protect the gastric mucosa merits consideration in the light of the present findings:
Search on Google
Index:
LILACS
Main subject:
Stomach Ulcer
/
Zinc
/
Ethanol
/
Gastric Mucosa
Limits:
Animals
Language:
En
Journal:
Braz. j. med. biol. res
Journal subject:
BIOLOGIA
/
MEDICINA
Year:
1989
Type:
Article
/
Project document