Nonfatal demyelinating encephalomyelitis induced by coronavirus (JHM strain) infection in mice
Braz. j. med. biol. res
; 22(1): 77-80, 1989. ilus, tab
Article
in En
| LILACS
| ID: lil-67485
Responsible library:
BR26.1
ABSTRACT
C3H mice infected intravenously with the JHM strain of coronavirus showed high incidence of demyelination (44.8%) and low incidence of encephalitis-induced mortality (6.9%). High titers of virus were detectable in the brain and liver of mice only during the first 3 to 12 days of infection (10 and 10 PFU/g, respectively). Most of the animals recovered from the first phase of disease and some (1.1%) came down with paralysis 6 to 7 weeks after the infection, with no histological changes or virus detectable in their tissues
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Index:
LILACS
Main subject:
Demyelinating Diseases
/
Coronavirus Infections
/
Coronaviridae
/
Encephalomyelitis
Limits:
Animals
Language:
En
Journal:
Braz. j. med. biol. res
Journal subject:
BIOLOGIA
/
MEDICINA
Year:
1989
Type:
Article
/
Congress and conference
/
Project document