Study of DLTH inhibiting RA by regulating immune function and cartilage degradation / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 624-630, 2021.
Article
in Zh
| WPRIM
| ID: wpr-1014409
Responsible library:
WPRO
ABSTRACT
Aim To observe the immune regulation and cartilage protection of dexamethasone-loaded thermosensitive hydrogel (DLTH) on rheumatoid arthritis (RA) rats via conceiving a newly injectable sustained DLTH with chitosan-glycerin-borax as carrier. Methods Thirty rats were randomly divided into three groups, namely control, model and DLTH group. RA model was established through immune induction in model and DLTH group. From the 12th day, rats of DLTH group were injected with 40 (jlL DLTH (1 mg · kg
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Pharmacological Bulletin
Year:
2021
Type:
Article