Mechanism of action and clinical significance of CST1 in the progression of gastric cancer / 国际肿瘤学杂志
Journal of International Oncology
; (12): 489-492, 2023.
Article
in Zh
| WPRIM
| ID: wpr-1018124
Responsible library:
WPRO
ABSTRACT
Cysteine protease inhibitor 1 (CST1) is a member of type 2 Cystatins superfamily, plays a key role in targeted regulation. CST1 is highly expressed in gastric cancer, promotes tumor cell migration and invasion by activating the epithelial-mesenchymal transformation pathway and Wnt pathway, and regulates tumor growth and progression in combination with the corresponding target genes of homeobox C10 and glutathione peroxidase 4. A deeper understanding of the role and function of CST1 in gastric cancer will help to further develop potential therapeutic targets and diagnostic and prognostic markers for gastric cancer.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Journal of International Oncology
Year:
2023
Type:
Article