A Case of Acute Cholestatic Hepatitis Associated with Orlistat / 대한간학회지
The Korean Journal of Hepatology
;
: 317-320, 2002.
Article
in Korean
| WPRIM
| ID: wpr-117146
ABSTRACT
Orlistat(Xenical(R), Roche) is considered a safe and effective drug to treat obesity by reduced absorption of 30% digested fat. To date, no serious adverse effects affecting the liver have been published except a case of subacute hepatic failure leading to liver transplantation in a young women with moderate obesity treated with orlistat. We report a case of acute cholestatic hepatitis in a young woman with moderate obesity treated with orlistat a 33-year-old female admitted for the evaluation of jaundice. Abdominal ultrasonography, ERCP, routine chemistry, viral markers, and a fine needle biopsy of liver were performed. Microscopic findings of the liver biopsy specimen were compatible with acute cholestatic hepatitis. After steroid therapy, liver function was improved.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
English Abstract
/
Cholestasis
/
Acute Disease
/
Anti-Obesity Agents
/
Chemical and Drug Induced Liver Injury
/
Lactones
/
Lipase
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
The Korean Journal of Hepatology
Year:
2002
Type:
Article
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