Transient Bullous Dermolysis of the Newborn / 대한피부과학회지
Korean Journal of Dermatology
; : 40-44, 2013.
Article
in Ko
| WPRIM
| ID: wpr-157630
Responsible library:
WPRO
ABSTRACT
Transient bullous dermolysis of the newborn (TBDN) is a rare subtype of the dystrophic epidermolysis bullosa characterized by blistering at birth which improves spontaneously during early life. Electron microscopy showed sublamina densa separation with dilated rough endoplasmic reticulum and electron dense inclusions. Immunofluorescence mapping using anti-type VII collagen antibody showed widespread intraepidermal type VII collagens which are a characteristic finding of TBDN. Here, we report two cases of TBDN presenting typical clinical manifestations, electron microscopy findings, and immunofluorescence mapping results. The skin lesions of both patients healed spontaneously 2~3 months later.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Skin
/
Microscopy, Electron
/
Epidermolysis Bullosa Dystrophica
/
Fluorescent Antibody Technique
/
Blister
/
Collagen
/
Endoplasmic Reticulum, Rough
/
Collagen Type VII
/
Parturition
/
Electrons
Limits:
Humans
/
Newborn
Language:
Ko
Journal:
Korean Journal of Dermatology
Year:
2013
Type:
Article