A Case of Gastric Adenocarcinoma in a Patient with X-linked Agammaglobulinemia / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy
; : 27-30, 2010.
Article
in Ko
| WPRIM
| ID: wpr-194421
Responsible library:
WPRO
ABSTRACT
X-linked agammaglobulinemia is a common type of primary immunodeficiency disorder that's caused by mutation of the BTK gene. The absence of B lymphocytes and plasma cells causes recurrent infections. Patients with X-linked agammaglobulinemia also have a high risk for developing hematological malignancies and, to a lesser degree, carcinoma. We report here on a 26-years-old male patient who suffered with X-linked agammaglobulinemia that was caused by BTK gene mutation, and he developed a gastric cancer in the antrum. He was noted to have chronic atrophic gastritis and diffuse intestinal metaplasia on the endoscopic examination that was done 7 years previously. We recommend regular esophagogastroduodenoscopic evaluation for a patient with X-linked agammaglobulinemia in order to make an early diagnosis of stomach carcinoma.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Plasma Cells
/
Stomach
/
Stomach Neoplasms
/
B-Lymphocytes
/
Adenocarcinoma
/
Hematologic Neoplasms
/
Agammaglobulinemia
/
Genetic Diseases, X-Linked
/
Early Diagnosis
/
Gastritis, Atrophic
Type of study:
Diagnostic_studies
/
Screening_studies
Limits:
Humans
/
Male
Language:
Ko
Journal:
Korean Journal of Gastrointestinal Endoscopy
Year:
2010
Type:
Article